Dr. Sachin Babasaheb Puri

Experience               : 1.8-year Industry (R&D synthesis)

Interest areas

• Development of novel NCEs
• In silico- based drug designing
• Medicinal Chemistry: SAR development; Hit to lead library generation
• Heterocyclic Synthesis and Functionalization
• Cell line studies

Research

• Presentations- Total number (5) 
• Patents- 01(Granted) and 01(published)
• Publications – Total number (International- 9, National-0)

Conferences/Workshops/Seminars attended- 05

1. Sachin Puri and Kapil Juvale, "Indole -9-cyanarylate Derivatives as Potent Inhibitors of Monocarboxylate transporter 1” at the International Conference on Drug Discovery –2022” organized by BITS Pilani, K. K Birla Goa campus on 10th and 11th Nov 2022.
2. Poster presented at Ramanbhai Foundation 9th International Symposium” on "Advances in New Drug Discovery and Development” organized at Zydus Research Centre Sarkhej Bavla Road, Moraiya, Ahmedabad, on February 6-8, 2020
3. Poster Presented at the Royal Society of Chemistry sponsored symposium on "Recent Advances in Organic & Bio-organic Chemistry” organized at IISER Mohali, Chandigarh, Punjab, on from 22^nd to 24^th March 2019.
4. Poster presented on National Conference on Chemistry of Materials &    Biologicals, 4th & 5th Jan, 2018, IIT Gandhinagar, India.
5. Attended one day symposium on stem cells and cancer, held at Somaiya Vidyavihar Mumbai on 5^th February 2018.

• Awards:

1. GPAT: Qualified
2. NIPER: Qualified
3. Selected Junior Research fellow under SERB sponsored research project of Dr. Kapil Juvale at SVKM’s, NMIMS, SPPSPTM, Mumbai campus (September 2017- February 2021)
4. Selected as Junior Research fellow, project sponsored by Drugs for Neglected Disease initiative (DNDi), Geneva, Switzerland (March 2021- April 2023)
5. Secured Second position in Quiz Competition, organized by Indian Pharmaceutical Association in 2014

•  
• Professional Memberships
• Registered Pharmacist (Maharashtra State pharmacy Council)
•  Recent Publications:

1. Sachin Puri, Katja Stefanb, Sharuk L. Khan Jens Pahnke, Sven Marcel Stefan*, Kapil Juvale* Indole Derivatives as New Structural Class of Potent and Antiproliferative Inhibitors of Monocarboxylate Transporter 1 (MCT1; SLC16A1), Journal of Medicinal chemistry 2023, 66, 1, 657–676. https://doi.org/10.1021/acs.jmedchem.2c01612 (Impact factor: 8.01)
2. Sachin Puri.; Kapil Juvale. * Facile synthesis of new N1-alkylated 1H-indazole-3- carboxamide derivatives as potential anticancer agents: in vitro, ADMET prediction, and SAR studies, Journal of molecular structure 1269,133727. https://doi.org/10.1016/j.molstruc.2022.133727 (Impact Factor: 3.84) 
3. Sachin Puri.; Iqrar Ahmed, Harun patel, Kapil kumar*, Kapil Juvale. * Evaluation of oxindole derivatives as a potential anticancer agent against breast carcinoma cells: In vitro, in silico, and molecular docking study, Toxicology in vitro, 2023, 86, 105517.https://doi.org/10.1016/j.tiv.2022.105517 (impact factor 3.68) 
4. Sachin Puri.; Nilesh S. Patil.; Kapil Juvale. * Investigation of some diethyl (4- (dimethylamino)-2,5-dihydro-2,5-dioxo-1-phenyl-1H-pyrrol-3-yl)(hydroxy) methylphosphonate derivatives for In silico pharmacokinetic profile and In vitro anticancer activity Chemical paper. 2022. 76, 1313-1321 https://doi.org/10.1007/s11696-022- 02329-3 (Impact Factor :2.14) 
5. Sachin Puri.; Kapil Juvale. * Monocarboxylate transporter 1 and 4 inhibitors as potential therapeutics for treating solid tumours: A review with structure-activity relationship insights. European Journal of Medicinal Chemistry. 2020, 199, 112393. https://doi.org/10.1016/j.ejmech.2020.112393 (Impact factor: 7.08). 
6. Sachin Puri.; Siddhi sawant.; Kapil Juvale. * " A comprehensive review on the indazole based derivatives as targeted anticancer agents, "Journal of molecular structure, 1284, 135327. https://doi.org/10.1016/j.molstruc.2023.135327 (Impact factor- 3.81) 
7. S.Baig, Sachin puri et.al. "Surface decorated quantum dots: Synthesis, properties and role in herbal therapy” Frontiers in Cell and Developmental Biology, 11, 1139671. https://doi.org/10.3389/fcell.2023.1139671 (Impact factor- 5.5) 
8. Sachin Puri, Tanuja Yadav, Mangilal Chouhan, Kapil Kumar, "Synthetic and Clinical Perspectives of EVOTAZ: An Overview” Mini-Reviews in Medicinal Chemistry,24(4),372-390. https://doi.org/10.2174/1389557523666230707151553 (Impact factor: 3.8) 
9. Sachin Puri, Namita Hegde, Siddhi Sawant, Ganesh Latambale, Kapil Juvale "Applications of phytochemicals in cancer therapy and anticancer drug development”, Recent Frontiers of Phytochemicals, 335-351. https://doi.org/10.1016/B978-0-443- 19143-5.00026-8. 

• Google Scholar ID: https://scholar.google.com.eg/citations?user=xjdsk5QAAAAJ&hl=en
• ORCID ID: 000-0001-6460-1444